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All issuesVolume 342, Issue 3IT NewsCxO

Rethinking and Realigning IT for the Agentic AI Era

CIO, Monday, September 14th, 2026

IT leaders adapt organizational structures and workflows to harness agentic AI's potential for business transformation.

As enterprises adopt agentic AI systems that autonomously execute workflows and make decisions, IT leaders are fundamentally restructuring operations, data governance, and team roles.

Organizations like Palo Alto Networks, CCS, and Gusto highlight key challenges: implementing robust testing infrastructure, establishing human-in-the-loop guardrails, managing data integrity, and redefining developer skills.

Success requires deep process reimagination, continuous agent evaluation, and collaboration between IT and business stakeholders to identify high-ROI use cases while maintaining security and accountability.

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